Sasamine was born on March 4, 1978 in Aira, Kagoshima, Japan. She attended elementary, middle, and high school in Aira.
She began acting in 1993 with the television drama, Red Labyrinth. Sasamine made her film debut in a small role as Yuki Matsuoka in Hana Yori Dango (1995). In recent years, she has appeared in various variety shows.
She married fellow actor, Masaki Miura (
|1995||Hana Yori Dango||Yuki Matsuoka|
|2010||Gegege no Nyobo|